Using Todays Anti Aging Supplements

Boldenone, also known as Bolden, is an anabolic steroids, and the anabolic, steroid androsterone, of the testosterone family. Boldenone itself hasn’t been marketed widely; as an over the counter pharmaceutical drug, it’s typically utilized as theroxine ester, or modestly androsterically available as Boldenone methyl, or as Boldenone propionate. This is typically sold in combination products with other anti aging Boldenone supplements, such as antioxidants, and as a dietary supplement. There have been no adverse clinical trials involving Boldenone in humans.

5 Things Athletes Should Know About Boldenone | USADA

The primary compound found in boldenone is its isoleucine, which is formed when the isolevulinic acid is broken down by an enzyme called the isopeptidin. Isoleucine is then combined with TCA (Triglyceride Chondroitin) in order to produce the active ingredient boldenone . The mechanism of action of this compound is through inhibition of glycolysis, where the glycolysis is controlled by oxygen. Glycolysis is central to a number of processes in the horse’s body, including wound healing, maintenance of tissue health and active transport in muscles. It is also important to note that, in addition to the glycolysis regulation, the kidneys play an essential role in the management of the amount of oxygen in the blood.

There are a number of potential side effects associated with using Boldenone in horses. One of the more common side effects of Boldenone use is the elevation of plasma testosterone levels above the low androgenic potency. Many in the horse community feel that elevating testosterone above the low androgenic potency is therapeutic, but others argue that while it may be therapeutic for acute situations, long term usage could result in hypogonadism or testicular feminization (the reduction of the male hormone testosterone). If the testosterone is exposed to multiple pathways, including the adrenals and the thyroid, the impact on these other organs could be even more adverse. This is why it has only been recently that Boldenone use has been approved by the U.S Food and Drug Administration.

There are some mild side effects noted when using Boldenone in horses however, including a reduced ability to retain water and increased urine production. These side effects can usually be resolved by discontinuing use. Other side effects noted include gastrointestinal problems, dehydration, and liver disease, but these are generally mild and are also reversible if discontinued early.

Another potential area of concern with using Boldenone for performance enhancement is the possibility of exposing the horses themselves to unnecessary levels of testosterone (testosterone is naturally produced in the testicles and adrenal glands and the amounts in body fluids). This is because exposing male horses to high levels of THT in their urine increases the risk of them developing male reproductive diseases like sperm abnormalities and testicular feminization. Such issues are not completely avoidable and it is recommended that before using boldenone for competitions in international races, a thorough blood profile be carried out to asses the blood testosterone levels in the animals. It is also recommended that a discussion be had with your veterinarian about the possible implications of such supplementation on the well-being of your horse. It is worth noting that this condition is extremely common in free-riding horses and that some free-riding horses may be suffering from a condition that may make them more susceptible to testosterone administration via the urethra.

An interesting area of controversy concerning the use of testosterone boosters like Boldenone is whether it is okay to use an ingredient known as bicalutamide, also known as “Bax hydrochloride”. Some sources believe that bicalutamide is okay to use while others claim that it can cause a variety of negative side effects in horses with prostate disorders such as prostatitis, incontinence or serum loperamide. In 2021, the American Association of Housekeeping questioned the use of bicarbonate as an ingredient in testosterone preparations for the horses it manages due to fears that the substance might have adverse effects on the prostate gland, which is part of the large intestine. The association further suggested that the horse would become obese due to excessive fat accumulation. Subsequently, the association called for a ban on bicalutamide use in its compounds.

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